Cav1.3

CACNA1D
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3LV3
Identifiers
Aliases	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, PASNA, SANDD, calcium voltage-gated channel subunit alpha1 D
External IDs	MGI: 88293 HomoloGene: 578 GeneCards: CACNA1D
Gene ontology Molecular function • calcium channel activity • metal ion binding • voltage-gated ion channel activity • high voltage-gated calcium channel activity • ion channel activity • voltage-gated calcium channel activity involved in cardiac muscle cell action potential • alpha-actinin binding • ankyrin binding • voltage-gated calcium channel activity • voltage-gated calcium channel activity involved SA node cell action potential Cellular component • voltage-gated calcium channel complex • L-type voltage-gated calcium channel complex • integral component of membrane • membrane • plasma membrane • Z disc Biological process • regulation of atrial cardiac muscle cell membrane repolarization • regulation of insulin secretion • adenylate cyclase-modulating G-protein coupled receptor signaling pathway • calcium ion import • regulation of ion transmembrane transport • ion transport • cardiac conduction • calcium ion transmembrane transport • transmembrane transport • regulation of potassium ion transmembrane transporter activity • transport • membrane depolarization during cardiac muscle cell action potential • regulation of potassium ion transmembrane transport • calcium ion transport • positive regulation of calcium ion transport • sensory perception of sound • cardiac muscle cell action potential involved in contraction • membrane depolarization during SA node cell action potential • regulation of heart rate by cardiac conduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	776	12289
Ensembl	ENSG00000157388	ENSMUSG00000015968
UniProt	Q01668	Q99246
RefSeq (mRNA)	NM_000720 NM_001128839 NM_001128840	NM_001083616 NM_028981 NM_001302637
RefSeq (protein)	NP_000711 NP_001122311 NP_001122312	NP_001077085.1 NP_001289566.1 NP_083257.2 NP_001077085 NP_001289566 NP_083257
Location (UCSC)	Chr 3: 53.33 – 53.81 Mb	Chr 14: 30.04 – 30.49 Mb
PubMed search

3LV3

776

12289

ENSG00000157388

ENSMUSG00000015968

Q01668

Q99246

NM_000720
NM_001128839
NM_001128840

NM_001083616
NM_028981
NM_001302637

NP_000711
NP_001122311
NP_001122312

NP_083257

Calcium channel, voltage-dependent, L type, alpha 1D subunit (also known as Ca_v1.3) is a protein that in humans is encoded by the CACNA1D gene. Ca_v1.3 channels belong to the Ca_v1 family, which form L-type calcium currents and are sensitive to selective inhibition by dihydropyridines (DHP).

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Wikipedia