Coxsackie virus and adenovirus receptor

CXADR

Protein CXADR PDB 1eaj.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1EAJ, 1F5W, 1JEW, 1KAC, 1P69, 1P6A, 1RSF, 2J12, 2J1K, 2NPL, 2W9L, 2WBW, 3J6L, 3J6M, 3J6N, 3J6O

Identifiers

CXADR, CAR, CAR4/6, HCAR, coxsackie virus and adenovirus receptor

External IDs

MGI: 1201679 HomoloGene: 1024 GeneCards: CXADR

Gene ontology
Molecular function	• PDZ domain binding • beta-catenin binding • connexin binding • virus receptor activity • integrin binding • protein binding • identical protein binding • receptor binding • cell adhesion molecule binding • cell adhesive protein binding involved in AV node cell-bundle of His cell communication
Cellular component	• cytoplasm • integral component of membrane • cell body • membrane • intercalated disc • cell-cell junction • bicellular tight junction • filopodium • growth cone • adherens junction • neuromuscular junction • plasma membrane • integral component of plasma membrane • nucleoplasm • protein complex • extracellular region • cell junction • apicolateral plasma membrane • basolateral plasma membrane • acrosomal vesicle • membrane raft • neuron projection • extracellular space • cell-cell adherens junction
Biological process	• actin cytoskeleton reorganization • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • cell-cell junction organization • epithelial structure maintenance • AV node cell to bundle of His cell communication • gamma-delta T cell activation • mitochondrion organization • neutrophil chemotaxis • transepithelial transport • cardiac muscle fiber development • homotypic cell-cell adhesion • heart development • cell adhesion • defense response to virus • regulation of immune response • viral entry into host cell • viral process • leukocyte migration • germ cell migration • AV node cell-bundle of His cell adhesion involved in cell communication • regulation of AV node cell action potential
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CXADR 203917 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


1525


13052


ENSG00000154639


ENSMUSG00000022865


P78310


P97792

RefSeq (mRNA)


NM_001207063 NM_001207064 NM_001207065 NM_001207066 NM_001338


NM_001025192 NM_001276263 NM_009988

RefSeq (protein)


NP_001193992 NP_001193993 NP_001193994 NP_001193995 NP_001329

NP_001020363.1 NP_001263192.1 NP_034118.1 NP_001020363 NP_001263192
NP_034118

Location (UCSC)

Chr 21: 17.51 – 17.59 Mb

Chr 16: 78.3 – 78.36 Mb

PubMed search

1EAJ, 1F5W, 1JEW, 1KAC, 1P69, 1P6A, 1RSF, 2J12, 2J1K, 2NPL, 2W9L, 2WBW, 3J6L, 3J6M, 3J6N, 3J6O

ENSG00000154639

ENSMUSG00000022865

NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338

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Wikipedia

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