DNA-3-methyladenine glycosylase

MPG
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1BNK, 1EWN, 1F4R, 1F6O, 3QI5, 3UBY
Identifiers
Aliases	MPG, AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg, N-methylpurine DNA glycosylase
External IDs	MGI: 97073 HomoloGene: 1824 GeneCards: MPG
Gene location (Human) Chr. Chromosome 16 (human) Band 16p13.3 Start 77,007 bp End 85,853 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11 A4|11 18.83 cM Start 32,226,505 bp End 32,232,700 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • DNA-7-methylguanine glycosylase activity • DNA-7-methyladenine glycosylase activity • damaged DNA binding • DNA binding • alkylbase DNA N-glycosylase activity • protein binding • DNA-3-methylguanine glycosylase activity • catalytic activity • hydrolase activity • DNA-3-methyladenine glycosylase activity • DNA N-glycosylase activity Cellular component • cytoplasm • mitochondrial nucleoid • mitochondrion • nucleus • nucleoplasm Biological process • depurination • DNA dealkylation involved in DNA repair • base-excision repair • cellular response to DNA damage stimulus • DNA repair Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4350	268395
Ensembl	ENSG00000103152	ENSMUSG00000020287
UniProt	P29372	Q04841
RefSeq (mRNA)	NM_002434 NM_001015052 NM_001015054	NM_010822
RefSeq (protein)	NP_001015052 NP_001015054 NP_002425	NP_034952
Location (UCSC)	Chr 16: 0.08 – 0.09 Mb	Chr 16: 32.23 – 32.23 Mb
PubMed search

1BNK, 1EWN, 1F4R, 1F6O, 3QI5, 3UBY

4350

268395

ENSG00000103152

ENSMUSG00000020287

P29372

Q04841

NM_002434
NM_001015052
NM_001015054

NM_010822

NP_001015052
NP_001015054
NP_002425

NP_034952

DNA-3-methyladenine glycosylase also known as 3-alkyladenine DNA glycosylase (AAG) or N-methylpurine DNA glycosylase (MPG) is an enzyme that in humans is encoded by the MPG gene.

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Wikipedia