Dextromethadone

Dextromethadone

Names
IUPAC name (6S)-6-(Dimethylamino)-4,4-diphenylheptan-3-one
Other names d-Methadone; 6S-Methadone; (+)-Methadone
Identifiers
CAS Number	5653-80-5
3D model (Jmol)	Interactive image
ChemSpider	559067
ECHA InfoCard	100.164.915
PubChem	643985
InChI InChI=1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3/t17-/m0/s1 Key: USSIQXCVUWKGNF-KRWDZBQOSA-N
SMILES CCC(=O)C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
Properties
Chemical formula	C21H27NO
Molar mass	309.45 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Dextromethadone is an antitussive opioid. It is the (S)-enantiomer of methadone.

D-Methadone acts as a N-methyl-D-aspartate NMDA receptor antagonist similar to Ketamine.

There is now an asymmetric synthesis available to prepare both dextromethadone [S-(+)-methadone] and levomethadone [R-(−)-methadone].