Duchess Marie Gabrielle in Bavaria (German: Marie Gabrielle Mathilde Isabelle Therese Antoinette Sabine Herzogin in Bayern) was born 9 October 1878 in Tegernsee in the Kingdom of Bavaria and died 24 October 1912 in Sorrento in the Kingdom of Italy).

Her parents were ophthalmologist Karl Theodor, Duke in Bavaria, a member of the House of Wittelsbach and kinsman of the Kings of Bavaria, and his second wife, Princess Maria José of Bragança, a daughter of King Miguel I, exiled monarch of Portugal. Her paternal aunt was Empress Elisabeth of Austria (Sissi) and one of her sisters was Elisabeth in Bavaria, consort of Albert I of Belgium. Brought up mainly in Possenhofen, she and her siblings had a happy childhood. She had an inclination for drawing, and in this was supported by her father.

On 10 July 1900 in Munich, Marie Gabrielle married her second cousin once-removed, Prince Rupprecht of Bavaria. He was the eldest son of Prince Ludwig of Bavaria (later Prince Regent and King of Bavaria) and Maria Theresia of Austria-Este. The wedding was attended by Prince Joachim of Prussia, representing his father Emperor Wilhelm II. After their marriage, the couple settled down in Bamberg, Bavaria, where Rupprecht was head of an army corps. Their two eldest children were born there.

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