EIF1AX

EIF1AX
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1D7Q, 3ZJY, 4KZY, 4KZZ
Identifiers
Aliases	EIF1AX, EIF1A, EIF1AP1, EIF4C, eIF-1A, eIF-4C, eukaryotic translation initiation factor 1A, X-linked
External IDs	MGI: 95298 HomoloGene: 20364 GeneCards: EIF1AX
Gene ontology Molecular function • translation factor activity, RNA binding • protein binding • translation initiation factor activity • RNA binding Cellular component • cytosol Biological process • translational initiation • translation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1964	13664
Ensembl	ENSG00000173674	ENSMUSG00000057561
UniProt	P47813	Q60872
RefSeq (mRNA)	NM_001412	NM_010120
RefSeq (protein)	NP_001403	NP_034250
Location (UCSC)	Chr X: 20.12 – 20.14 Mb	Chr 18: 46.6 – 46.61 Mb
PubMed search

1D7Q, 3ZJY, 4KZY, 4KZZ

1964

13664

ENSG00000173674

ENSMUSG00000057561

P47813

Q60872

NM_001412

NM_010120

NP_001403

NP_034250

Eukaryotic translation initiation factor 1A, X-chromosomal (eIF1A) is a protein that in humans is encoded by the EIF1AX gene. This gene encodes an essential eukaryotic translation initiation factor. The protein is a component of the 43S pre-initiation complex (PIC), which mediates the recruitment of the small 40S ribosomal subunit to the 5' cap of messenger RNAs.

eIF1A is a small proteins (17 kDa in budding yeast) and a component of the 43S preinitiation complexes (PIC). eIF1A binds near the ribosomal A-site, in a manner similar to the functionally related bacterial counterpart IF1.

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Wikipedia