EIF2S3

EIF2S3
Identifiers
Aliases	EIF2S3, EIF2, EIF2G, EIF2gamma, eIF-2gA, eukaryotic translation initiation factor 2 subunit gamma
External IDs	MGI: 1349431 HomoloGene: 90888 GeneCards: EIF2S3
Gene ontology Molecular function • nucleotide binding • GTP binding • translation factor activity, RNA binding • protein binding • translation initiation factor activity • GTPase activity • cadherin binding Cellular component • cytoplasm • cytosol • extracellular exosome • nucleus • eukaryotic translation initiation factor 2 complex Biological process • translational initiation • transmembrane transport • translation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1968	26905
Ensembl	ENSG00000130741	ENSMUSG00000035150
UniProt	P41091	Q9Z0N1
RefSeq (mRNA)	NM_001415	NM_012010
RefSeq (protein)	NP_001406 NP_001406.1	NP_036140.1 NP_036140
Location (UCSC)	Chr X: 24.05 – 24.08 Mb	Chr X: 94.19 – 94.21 Mb
PubMed search

1968

26905

ENSG00000130741

ENSMUSG00000035150

P41091

Q9Z0N1

NM_001415

NM_012010

NP_001406
NP_001406.1

NP_036140.1
NP_036140

Eukaryotic translation initiation factor 2 subunit 3 (eIF2γ) is a protein that in humans is encoded by the EIF2S3 gene.

Eukaryotic translation initiation factor 2 (eIF2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. eIF2 is composed of three subunits, alpha (α), beta (β), and gamma (γ, this article), with the protein encoded by this gene representing the gamma subunit.

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