| ELAVL3 | |||||||||||||||
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| Identifiers | |||||||||||||||
| Aliases | ELAVL3, HUC, HUCL, PLE21, ELAV like neuron-specific RNA binding protein 3 | ||||||||||||||
| External IDs | MGI: 109157 HomoloGene: 31035 GeneCards: ELAVL3 | ||||||||||||||
| RNA expression pattern | |||||||||||||||
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| Species | Human | Mouse | |||||||||||||
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| Location (UCSC) | Chr 19: 11.45 – 11.48 Mb | Chr 9: 22.02 – 22.05 Mb | |||||||||||||
| PubMed search | |||||||||||||||
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ELAV-like protein 3 is a protein that in humans is encoded by the ELAVL3 gene.
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.