EPHA7

EPHA7

Protein EPHA7 PDB 2REI.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2REI, 3DKO, 3H8M, 3NRU

Identifiers

EPHA7, EHK-3, EHK3, EK11, HEK11, EPH receptor A7

External IDs

MGI: 95276 HomoloGene: 20935 GeneCards: EPHA7

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • GPI-linked ephrin receptor activity • ephrin receptor binding • kinase activity • protein binding • transmembrane receptor protein tyrosine kinase activity • protein tyrosine kinase activity • ATP binding • axon guidance receptor activity • ephrin receptor activity • chemorepellent activity
Cellular component	• integral component of membrane • postsynaptic membrane • membrane • neuromuscular junction • plasma membrane • integral component of plasma membrane • neuronal cell body • dendrite
Biological process	• apoptotic process • positive regulation of protein phosphorylation • regulation of protein autophosphorylation • phosphorylation • transmembrane receptor protein tyrosine kinase signaling pathway • ephrin receptor signaling pathway • negative regulation of synapse assembly • regulation of cysteine-type endopeptidase activity involved in apoptotic process • nervous system development • branching morphogenesis of a nerve • multicellular organism development • protein phosphorylation • negative regulation of collateral sprouting • positive regulation of neuron apoptotic process • brain development • nephric duct morphogenesis • regulation of cell-cell adhesion • regulation of ERK1 and ERK2 cascade • positive regulation of apoptotic process • peptidyl-tyrosine phosphorylation • regulation of peptidyl-tyrosine phosphorylation • retinal ganglion cell axon guidance • negative chemotaxis
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE EPHA7 206852 at fs.png

More reference expression data

Orthologs

Species

Human

Mouse


2045


13841


ENSG00000135333


ENSMUSG00000028289


Q15375


Q61772

RefSeq (mRNA)


NM_001288629 NM_001288630 NM_004440


NM_001122889 NM_001290434 NM_010141

RefSeq (protein)


NP_001275558 NP_001275559 NP_004431


NP_001277363.1 NP_034271.3 NP_001116361 NP_001277363 NP_034271

Location (UCSC)

Chr 6: 93.24 – 93.42 Mb

Chr 4: 28.81 – 28.97 Mb

PubMed search

2REI, 3DKO, 3H8M, 3NRU

ENSG00000135333

ENSMUSG00000028289

NM_001288629
NM_001288630
NM_004440

NM_001122889
NM_001290434
NM_010141

NP_001275558
NP_001275559
NP_004431

NP_001277363.1
NP_034271.3
NP_001116361
NP_001277363
NP_034271

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Wikipedia

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