ETS1

ETS1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GVJ, 2NNY, 2STT, 2STW, 3MFK, 3RI4, 3WTS, 3WTT, 3WTU, 3WTV, 3WTW, 3WTX, 3WTY, 3WTZ, 3WU0, 3WU1, 4L0Y, 4L0Z, 4L18, 4LG0
Identifiers
Aliases	ETS1, ETS-1, EWSR2, p54, c-ets-1, ETS proto-oncogene 1, transcription factor
External IDs	MGI: 95455 HomoloGene: 3837 GeneCards: ETS1
Genetically Related Diseases
obesity, celiac disease, systemic lupus erythematosus
Gene ontology Molecular function • DNA binding • sequence-specific DNA binding • transcription factor activity, sequence-specific DNA binding • transcription factor binding • protein binding • histone acetyltransferase binding • identical protein binding • transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding • RNA polymerase II core promoter proximal region sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding • sequence-specific double-stranded DNA binding Cellular component • cytoplasm • transcription factor complex • nucleoplasm • nucleus Biological process • regulation of apoptotic process • pituitary gland development • response to estradiol • response to interleukin-1 • response to hypoxia • regulation of transcription, DNA-templated • positive regulation of erythrocyte differentiation • cell motility • estrous cycle • immune system process • regulation of transcription from RNA polymerase II promoter • response to antibiotic • female pregnancy • angiogenesis involved in wound healing • positive regulation of cell migration • response to mechanical stimulus • response to laminar fluid shear stress • negative regulation of cell cycle • regulation of angiogenesis • transcription from RNA polymerase II promoter • regulation of extracellular matrix disassembly • transcription, DNA-templated • positive regulation of angiogenesis • positive regulation of endothelial cell migration • positive regulation of transcription, DNA-templated • PML body organization • response to wounding • immune response • positive regulation of cell proliferation • hypothalamus development • positive regulation of cellular component movement • negative regulation of inflammatory response • positive regulation of transcription from RNA polymerase II promoter • negative regulation of cell proliferation • cellular response to hydrogen peroxide • positive regulation of inflammatory response • pri-miRNA transcription from RNA polymerase II promoter • positive regulation of leukocyte adhesion to vascular endothelial cell Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2113	23871
Ensembl	ENSG00000134954	ENSMUSG00000032035
UniProt	P14921	P27577
RefSeq (mRNA)	NM_001143820 NM_001162422 NM_005238 NM_001330451	NM_001038642 NM_011808
RefSeq (protein)	NP_001137292 NP_001155894 NP_001317380 NP_005229	NP_035938.2 NP_001033731 NP_035938
Location (UCSC)	Chr 11: 128.46 – 128.59 Mb	Chr 9: 32.64 – 32.76 Mb
PubMed search

1GVJ, 2NNY, 2STT, 2STW, 3MFK, 3RI4, 3WTS, 3WTT, 3WTU, 3WTV, 3WTW, 3WTX, 3WTY, 3WTZ, 3WU0, 3WU1, 4L0Y, 4L0Z, 4L18, 4LG0

2113

23871

ENSG00000134954

ENSMUSG00000032035

...
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