Estromustine

Estromustine
Pharmacokinetic data

Biological half-life	14 hours
Identifiers
IUPAC name [(8R,9S,13S,14S)-13-Methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] N,N-bis(2-chloroethyl)carbamate
Synonyms	Leo 271 f
CAS Number	62899-40-5
PubChem CID	124946
ChemSpider	111241
Chemical and physical data
Formula	C₂₃H₂₉Cl₂NO₃
Molar mass	438.38726 g/mol
3D model (Jmol)	Interactive image
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OC(=O)N(CCCl)CCCl
InChI InChI=1S/C23H29Cl2NO3/c1-23-9-8-18-17-5-3-16(29-22(28)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)27/h3,5,14,18-20H,2,4,6-13H2,1H3/t18-,19-,20+,23+/m1/s1 Key:AXWYROHIFVWHMR-UGTOYMOASA-N

Estromustine (developmental code name Leo 271 f), also known as estrone 17β-3-N-bis(2-chloroethyl)carbamate or estrone-cytostatic complex, is a major active metabolite of the cystotatic estrogen and nitrogen mustard alkylating antineoplastic agent estramustine phosphate, a drug used in the treatment of prostate cancer.