Etobicoke Centre (French: Etobicoke-Centre) is a federal electoral district in Ontario, Canada, that has been represented in the House of Commons of Canada since 1979.

The riding includes the neighbourhoods of Eatonville (part), Islington-City Centre West (part), Richview, Humber Heights - Westmount, Eringate – Centennial – West Deane, Markland Wood, Princess Gardens, Thorncrest Village and Humber Valley Village in the former city of Etobicoke, Toronto.

The riding was created in 1976 from part of the Etobicoke riding in what was then a constituent municipality of Metropolitan Toronto.

On May 18, 2012, the Ontario Superior Court declared the 2011 federal election results for this district to be null and void. The judge ruled that 79 votes should not have been counted when the margin of victory in the riding was only 26 votes. On May 28, 2012, however, the incumbent Member of Parliament, Ted Opitz, filed an appeal with the Supreme Court of Canada. On October 25, 2012, the Supreme Court allowed Mr. Opitz's appeal and quashed the order for a by-election. In its decision, the Supreme Court restored 59 of the 79 tossed votes, essentially leaving Mr. Optiz with a 6 vote margin of victory.

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