FGD3

FGD3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2COC
Identifiers
Aliases	FGD3, ZFYVE5, FYVE, RhoGEF and PH domain containing 3
External IDs	MGI: 1353657 HomoloGene: 22925 GeneCards: FGD3
Gene ontology Molecular function • metal ion binding • small GTPase binding • Rho guanyl-nucleotide exchange factor activity • guanyl-nucleotide exchange factor activity Cellular component • cytoplasm • cytosol • Golgi apparatus • ruffle • cytoskeleton • lamellipodium Biological process • regulation of GTPase activity • filopodium assembly • cytoskeleton organization • regulation of cell shape • positive regulation of apoptotic process • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • actin cytoskeleton organization • positive regulation of GTPase activity Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	89846	30938
Ensembl	ENSG00000127084	ENSMUSG00000037946
UniProt	Q5JSP0	O88842
RefSeq (mRNA)	NM_001083536 NM_001286993 NM_033086	NM_015759
RefSeq (protein)	NP_001077005 NP_001273922 NP_149077 NP_001077005.1 NP_149077.2	n/a
Location (UCSC)	Chr 9: 92.95 – 93.04 Mb	Chr 13: 49.26 – 49.32 Mb
PubMed search

2COC

89846

30938

ENSG00000127084

ENSMUSG00000037946

Q5JSP0

O88842

NM_001083536
NM_001286993
NM_033086

NM_015759

NP_001077005
NP_001273922
NP_149077
NP_001077005.1
NP_149077.2

n/a

FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene.

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