FGD4

Identifiers

FGD4, CMT4H, FRABP, ZFYVE6, FYVE, RhoGEF and PH domain containing 4

External IDs

Gene ontology
Molecular function	• metal ion binding • small GTPase binding • actin binding • Rho guanyl-nucleotide exchange factor activity • guanyl-nucleotide exchange factor activity
Cellular component	• cytoplasm • cytosol • Golgi apparatus • cell projection • filopodium • ruffle • cytoskeleton • lamellipodium
Biological process	• regulation of GTPase activity • filopodium assembly • cytoskeleton organization • regulation of cell shape • positive regulation of apoptotic process • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • actin cytoskeleton organization • positive regulation of GTPase activity
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


121512


224014


ENSG00000139132


ENSMUSG00000022788


Q96M96 Q49A55


Q91ZT5

RefSeq (mRNA)

NM_001304480 NM_001304481 NM_001304483 NM_001304484 NM_139241
NM_001330373 NM_001330374


NM_001301817 NM_001301818 NM_139232 NM_139233 NM_139234

RefSeq (protein)

NP_001291409 NP_001291410 NP_001291412 NP_001291413 NP_001317302
NP_001317303 NP_640334 NP_001291412.1


NP_001288746 NP_001288747 NP_631978

Location (UCSC)

PubMed search

FYVE, RhoGEF and PH domain-containing protein 4 is a protein that in humans is encoded by the FGD4 gene.