FNTB

FNTB

Protein FNTB PDB 1d8d.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1JCQ, 1LD7, 1LD8, 1MZC, 1S63, 1SA4, 1TN6, 2F0Y, 2H6F, 2H6G, 2H6H, 2H6I, 2IEJ, 3E37

Identifiers

FNTB, FPTB, farnesyltransferase, CAAX box, beta

External IDs

MGI: 1861305 HomoloGene: 1535 GeneCards: FNTB

Gene location (Human)

Chr.	Chromosome 14 (human)

Band	14q23.3	Start	64,986,720 bp
Band	14q23.3	End	65,062,652 bp

Gene location (Mouse)

Chr.	Chromosome 12 (mouse)

Band	12 C3\|12 33.73 cM	Start	76,765,589 bp
Band	12 C3\|12 33.73 cM	End	76,921,412 bp

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• farnesyltranstransferase activity • metal ion binding • transferase activity • drug binding • prenyltransferase activity • catalytic activity • zinc ion binding • isoprenoid binding • protein farnesyltransferase activity • peptide binding • protein binding
Cellular component	• cytosol • protein farnesyltransferase complex • microtubule associated complex • protein complex
Biological process	• negative regulation of cell proliferation • response to cytokine • wound healing • protein farnesylation • regulation of cell proliferation • response to organic cyclic compound • regulation of rhodopsin mediated signaling pathway • positive regulation of cell proliferation • response to inorganic substance • positive regulation of nitric-oxide synthase biosynthetic process • positive regulation of cell cycle • positive regulation of fibroblast proliferation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


2342


110606


ENSG00000257365


ENSMUSG00000033373


P49356


P49356 Q8K2I1

RefSeq (mRNA)


NM_002028


NM_145927

RefSeq (protein)


NP_002019


NP_002019 NP_666039

Location (UCSC)

Chr 14: 64.99 – 65.06 Mb

Chr 14: 76.77 – 76.92 Mb

PubMed search

1JCQ, 1LD7, 1LD8, 1MZC, 1S63, 1SA4, 1TN6, 2F0Y, 2H6F, 2H6G, 2H6H, 2H6I, 2IEJ, 3E37

ENSG00000257365

ENSMUSG00000033373

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Wikipedia

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