Ferruginol

Ferruginol

Names
IUPAC name (4bS,8aS)-4b,8,8-Trimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol
Identifiers
CAS Number	514-62-5 Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:78274 N
ChemSpider	390582 Y
PubChem CID	442027
InChI InChI=1S/C20H30O/c1-13(2)15-11-14-7-8-18-19(3,4)9-6-10-20(18,5)16(14)12-17(15)21/h11-13,18,21H,6-10H2,1-5H3/t18-,20+/m0/s1 Y Key: QXNWVJOHUAQHLM-AZUAARDMSA-N Y InChI=1/C20H30O/c1-13(2)15-11-14-7-8-18-19(3,4)9-6-10-20(18,5)16(14)12-17(15)21/h11-13,18,21H,6-10H2,1-5H3/t18-,20+/m0/s1 Key: QXNWVJOHUAQHLM-AZUAARDMBU
SMILES Oc1c(cc2c(c1)[C@]3(CCCC([C@@H]3CC2)(C)C)C)C(C)C
Properties
Chemical formula	C20H30O
Molar mass	286.45 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

Ferruginol is a natural phenol and a meroterpene (a chemical compound containing a terpenoid substructure) that has been isolated from the needles of the redwood Sequoia sempervirens. The terpenoid part is a diterpene of the abietane chemical class.

Research published in 2005 found that this and other compound of the class from Sequoia have anti-tumor properties, and showed in vitro human colon, breast, and lung tumor reduction and reduction in oncogene transformed cells as well. Specific activity of tumor growth inhibition (GI) is 2-5 micrograms/milliliter.

Ferruginol has also been found to have antibacterial activity. Gastroprotective effects of ferruginol have also been noted.