| Frederick Francis I | |
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| Grand Duke of Mecklenburg-Schwerin | |
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Portrait by Rudolph Suhrlandt (1817)
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| Reign | 24 April 1785 – 1 February 1837 |
| Predecessor | Frederick II |
| Successor | Paul Frederick |
| Born |
10 December 1756 Schwerin |
| Died | 1 February 1837 (aged 80) Ludwigslust |
| Spouse | Princess Louise of Saxe-Gotha-Altenburg |
| House | Mecklenburg-Schwerin |
| Father | Duke Louis of Mecklenburg-Schwerin |
| Mother | Princess Charlotte Sophie of Saxe-Coburg-Saalfeld |
| Religion | Lutheranism |
Frederick Francis I, Grand Duke of Mecklenburg-Schwerin (10 December 1756 – 1 February 1837) ruled over the German state of Mecklenburg-Schwerin, first as Duke (1785–1815), and then as Grand Duke (1815–1837).
He was born in Schwerin to Duke Louis of Mecklenburg-Schwerin and Princess Charlotte Sophie of Saxe-Coburg-Saalfeld. Friedrich Franz succeeded his uncle Friedrich as Duke of Mecklenburg-Schwerin in 1785.
Following the Napoleonic Wars, Friedrich Franz was raised to the dignity of Grand Duke at the Congress of Vienna. Along with his cousin in Mecklenburg-Strelitz, he was known as one of the most reactionary German rulers. On his death in 1837 he was succeeded by his grandson, Grand Duke Paul Friedrich.
On 1 June 1775 in Gotha, Friedrich Franz married Princess Louise of Saxe-Gotha-Altenburg. They had eight children: