GEFT

ARHGEF25
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2RGN
Identifiers
Aliases	ARHGEF25, GEFT, p63RhoGEF, Rho guanine nucleotide exchange factor 25
External IDs	MGI: 1277173 HomoloGene: 32691 GeneCards: ARHGEF25
Gene ontology Molecular function • Rho guanyl-nucleotide exchange factor activity • guanyl-nucleotide exchange factor activity Cellular component • cytoplasm • cytosol • plasma membrane • myofibril • sarcomere • membrane Biological process • positive regulation of GTPase activity • regulation of Rho protein signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	115557	52666
Ensembl	ENSG00000240771	ENSMUSG00000019467
UniProt	Q86VW2	Q9CWR0
RefSeq (mRNA)	NM_001111270 NM_133483 NM_182947 NM_001347933	NM_001166413 NM_028027
RefSeq (protein)	NP_001104740 NP_891992 NP_001334862	NP_001159885 NP_082303
Location (UCSC)	Chr 12: 57.61 – 57.62 Mb	Chr 10: 127.18 – 127.19 Mb
PubMed search

2RGN

115557

52666

ENSG00000240771

ENSMUSG00000019467

Q86VW2

Q9CWR0

NM_001111270
NM_133483
NM_182947
NM_001347933

NM_001166413
NM_028027

NP_001104740
NP_891992
NP_001334862

NP_001159885
NP_082303

RAC/CDC42 exchange factor, also known as GEFT, is a human gene.

GEFT has been shown to interact with RHOA.

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Wikipedia