GLRA3

GLRA3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5CFB
Identifiers
Aliases	GLRA3, glycine receptor alpha 3
External IDs	MGI: 95749 HomoloGene: 142 GeneCards: GLRA3
Gene ontology Molecular function • glycine-gated chloride ion channel activity • glycine binding • metal ion binding • transmitter-gated ion channel activity • chloride channel activity • extracellular ligand-gated ion channel activity • extracellular-glycine-gated chloride channel activity • ion channel activity Cellular component • integral component of membrane • perikaryon • postsynaptic membrane • cell projection • membrane • plasma membrane • synapse • integral component of plasma membrane • chloride channel complex • glycine-gated chloride channel complex • cell junction • dendrite Biological process • response to amino acid • chloride transmembrane transport • ion transport • ion transmembrane transport • transport • synaptic transmission, glycinergic • chloride transport • neuropeptide signaling pathway • protein homooligomerization • excitatory postsynaptic potential Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8001	110304
Ensembl	ENSG00000145451	ENSMUSG00000038257
UniProt	O75311	Q91XP5
RefSeq (mRNA)	NM_001042543 NM_006529	NM_080438
RefSeq (protein)	NP_001036008 NP_006520	NP_536686.2 NP_536686
Location (UCSC)	Chr 4: 174.64 – 174.83 Mb	Chr 8: 55.94 – 56.13 Mb
PubMed search

5CFB

8001

110304

ENSG00000145451

ENSMUSG00000038257

O75311

Q91XP5

NM_001042543
NM_006529

NM_080438

NP_001036008
NP_006520

NP_536686.2
NP_536686

The Glycine receptor subunit alpha-3 is a protein that in humans is encoded by the GLRA3 gene. The protein encoded by this gene is a subunit of the glycine receptor.

Variants of this receptor subunit is associated with susceptibility to epilepsy.

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Wikipedia