GPR81

HCAR1
Identifiers
Aliases	HCAR1, GPR104, GPR81, HCA1, LACR1, TA-GPCR, TAGPCR, FKSG80, hydroxycarboxylic acid receptor 1
External IDs	MGI: 2441671 HomoloGene: 13060 GeneCards: HCAR1
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • G-protein coupled receptor signaling pathway • signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27198	243270
Ensembl	ENSG00000196917	ENSMUSG00000049241
UniProt	Q9BXC0	Q8C131
RefSeq (mRNA)	NM_032554	NM_175520
RefSeq (protein)	NP_115943	NP_780729
Location (UCSC)	Chr 12: 122.73 – 122.73 Mb	Chr 5: 123.88 – 123.88 Mb
PubMed search

27198

243270

ENSG00000196917

ENSMUSG00000049241

Q9BXC0

Q8C131

NM_032554

NM_175520

NP_115943

NP_780729

G protein-coupled receptor 81, also known as GPR81, is a protein that in humans is encoded by the GPR81 gene.

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.

Lactate activates the GPR81 receptor which in turn inhibits lipolysis in fat cells.

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Wikipedia