Galactose-1-phosphate uridylyltransferase

GALT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5IN3
Identifiers
Aliases	GALT, entrez:2592
External IDs	OMIM: 606999 MGI: 95638 HomoloGene: 126 GeneCards: GALT
Gene ontology Molecular function • transferase activity • nucleotidyltransferase activity • zinc ion binding • protein binding • catalytic activity • metal ion binding • UDP-glucose:hexose-1-phosphate uridylyltransferase activity Cellular component • cytosol • Golgi apparatus Biological process • UDP-glucose catabolic process • galactose metabolic process • galactose catabolic process • carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2592	14430
Ensembl	ENSG00000213930	ENSMUSG00000036073
UniProt	P07902	Q03249
RefSeq (mRNA)	NM_001258332 NM_000155	NM_016658 NM_001302511
RefSeq (protein)	NP_000146 NP_001245261	NP_057867.2 NP_001289440 NP_057867
Location (UCSC)	Chr 9: 34.64 – 34.65 Mb	Chr 4: 41.76 – 41.76 Mb
PubMed search

Galactose-1-phosphate uridyl transferase, C-terminal domain
structure of nucleotidyltransferase complexed with udp-galactose
Identifiers
Symbol	GalP_UDP_tr_C
Pfam	PF02744
Pfam clan	CL0265
InterPro	IPR005850
PROSITE	PDOC00108
SCOP	1hxp
SUPERFAMILY	1hxp
Available protein structures: Pfam structures PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

5IN3

2592

14430

ENSG00000213930

ENSMUSG00000036073

P07902

Q03249

NM_001258332
NM_000155

NM_016658
NM_001302511

NP_000146
NP_001245261

NP_057867.2
NP_001289440
NP_057867

Galactose-1-phosphate uridylyltransferase (or GALT) is an enzyme (EC 2.7.7.12) responsible for converting ingested galactose to glucose.

Galactose-1-phosphate uridylyltransferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely: