Hüseyin Avni Pasha (1820, Isparta – June 15th 1876, Istanbul) was an Ottoman statesman. He was Grand Vizier of the Ottoman Empire from 15 February 1874 to 26 April 1875. He was killed by Çerkess Hassan the younger brother of Neşerek Kadın Efendi, who accused him of the murder of Ottoman Sultan Abdülaziz, on 15 June 1876 during a cabinet meeting of Ottoman Sultan Mehmed Murad V at the Palace of Midhat Pasha near Beyazıt in Fatih, Istanbul.