HEXB

HEXB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1NOU, 1NOW, 1NP0, 1O7A, 2GJX, 2GK1, 3LMY, 5BRO
Identifiers
Aliases	HEXB, ENC-1AS, HEL-248, HEL-S-111, hexosaminidase subunit beta
External IDs	OMIM: 606873 MGI: 96074 HomoloGene: 437 GeneCards: HEXB
Gene ontology Molecular function • acetylglucosaminyltransferase activity • hydrolase activity, hydrolyzing O-glycosyl compounds • protein homodimerization activity • hydrolase activity, acting on glycosyl bonds • beta-N-acetylhexosaminidase activity • protein heterodimerization activity • hydrolase activity Cellular component • membrane • azurophil granule • acrosomal vesicle • lysosomal lumen • lysosome • extracellular exosome • extracellular region • extracellular space • azurophil granule lumen Biological process • skeletal system development • cellular protein metabolic process • hyaluronan catabolic process • sexual reproduction • glycosphingolipid metabolic process • locomotory behavior • neuromuscular process controlling balance • astrocyte cell migration • lipid storage • cellular calcium ion homeostasis • sensory perception of sound • regulation of cellular metabolic process • single fertilization • oogenesis • neuromuscular process • male courtship behavior • keratan sulfate catabolic process • regulation of cell shape • phospholipid biosynthetic process • chondroitin sulfate catabolic process • myelination • oligosaccharide catabolic process • metabolic process • lysosome organization • penetration of zona pellucida • ganglioside catabolic process • positive regulation of transcription from RNA polymerase II promoter • glycosaminoglycan metabolic process • carbohydrate metabolic process • neutrophil degranulation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3074	15212
Ensembl	ENSG00000049860	ENSMUSG00000021665
UniProt	P07686	P20060
RefSeq (mRNA)	NM_001292004 NM_000521	NM_010422
RefSeq (protein)	NP_000512 NP_001278933	NP_034552.1 NP_034552
Location (UCSC)	Chr 5: 74.64 – 74.72 Mb	Chr 13: 97.18 – 97.2 Mb
PubMed search

1NOU, 1NOW, 1NP0, 1O7A, 2GJX, 2GK1, 3LMY, 5BRO

3074

15212

ENSG00000049860

ENSMUSG00000021665

P07686

P20060

NM_001292004
NM_000521

NM_010422

NP_000512
NP_001278933

NP_034552.1
NP_034552

Beta-hexosaminidase subunit beta is an enzyme that in humans is encoded by the HEXB gene.

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