Hairy (gene)

Hairy RNA localisation element (HLE)
Predicted secondary structure and sequence conservation of HLE
Identifiers
Symbol	HLE
Rfam	RF00437
Other data
RNA type	Cis-reg
Domain(s)	Eukaryota
SO	0000233

The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery. HLE is found in Drosophila species.