Haplogroup O-M176

Haplogroup O-M176 O1b2 M176
Possible time of origin	28,500 [95% CI 26,200 <-> 30,900] years before present
Possible place of origin	Korean Peninsula, Manchuria or a nearby part of northern East Asia
Coalescence age	12,100 [95% CI 9,700 <-> 14,600] years before present (YFull) 6,300 [95% CI 600–37,000] years ago (Katoh 2004)
Ancestor	O-P31
Defining mutations	M176/SRY465, P49, 022454
Highest frequencies	Koreans, Japanese, Ryukyuans, Manchus Japanese 32% 26% (Jin 2003) (Jin 2009)-36% (Katoh 2004) South Koreans 30% 19% (Jin 2003) -37% (Park 2013) Okinawans 27% 22% (Hammer 2006)-31% (Mizuno 2008) Manchus 19% 4% (Karafet 2001)-34% (Katoh 2004)

Haplogroup O-47z O1b2a1-47z
Possible time of origin	7,870 [95% CI 5,720–12,630] years ago (Hammer 2006) 8,200 [95% CI 6,300 <-> 10,200] ybp
Possible place of origin	Japanese Archipelago(Hammer 2006)　or　Korean Peninsula(see Jin 2003)
Ancestor	O-M176
Defining mutations	47z
Highest frequencies	Japanese, Ryukyuans, Koreans, Manchus Japanese 24% Range: 19% (Jin 2003) to 29% (Katoh 2004) Okinawans 17% Range: 11% (Hammer 2006) to 20% (Nonaka 2007) South Koreans 8% Range: 4% (Hammer 2006 and Karafet 2001) to 12% (Xue 2006) Manchus 7% Range: 0% Karafet 2001, Hammer 2006, and Xue 2006 to 19% (Jin 2009)

Haplogroup O-F940 O2b1b2-F940
Possible time of origin	3,500 [2,000-13,000]
Possible place of origin	Manchuria or Korean Peninsula
Ancestor	O-F2868
Defining mutations	CTS12145, F1912, F2206, F2703, F940, K3
Highest frequencies	Manchurian, Manchu Mongolian, Manchu Han Manchus 0-26% (katoh et al 2005) Manchu Mongolian 0-4% (Guo et al 2015) Manchu Han 0-4% (Liu et al 2014)

Haplogroup O-L682 O1b2a2a-L682
Possible time of origin	6,300 [95% CI 4,700 <-> 8,000] ybp
Possible place of origin	Korean Peninsula or Manchuria
Ancestor	O-M176, O-F3356
Defining mutations	L682
Highest frequencies	Koreans, Hezhen, Udege, Japanese, Ryukyuans, Manchus South Koreans 20% Range: 20% Katoh 2004 to 21% (Yoo 2014) Okinawans 12% Range: 11% (Mizuno 2008) to 12% (Hashiyada 2008) Hezhen 8% Range: 4% (Xue 2006) to 12% (HGDP 2009) Japanese 6% Range: 6% (Katoh 2004) to 7% (Hashiyada 2008) Manchus 3% 6% (Katoh 2004) Udeges 10% (Jin 2010)

Koreans, Japanese, Ryukyuans, Manchus

In human population genetics, Y-Chromosome haplogroups define the major lineages of direct paternal (male) lines back to a shared common ancestor in Africa. Haplogroup O-M176 (aka O-SRY465) is a human Y-chromosome DNA haplogroup. It is best known for its part in the settlement of Korea and Japan. It is a descendant of Haplogroup O-P31, and it has been estimated to share a most recent common ancestor with its nearest outgroup, Haplogroup O-K18, approximately 28,500 [95% CI 26,200 <-> 30,900] years before present.

Haplogroup O-M176 is found mainly in the northernmost parts of East Asia, from the Uriankhai and Zakhchin peoples of western Mongolia (Katoh 2004) to the Japanese of Japan, though it also has been detected sporadically in the Buryats (Jin 2003). It's been detected with moderate frequencies in Udegeys (Jin 2010) of southern Siberia, rarely among populations of Southeast Asia including Indonesia (Hammer 2006 and Jin 2003), the Philippines (Jin 2003), Thailand (Jin 2003), and Vietnam (Hammer 2006 and Jin 2003), and Micronesians (Hammer 2006). This haplogroup is found with its highest frequency and diversity values among modern populations of Japan and Korea and is absent from most populations in China, but it has been detected in some samples of Han Chinese from Beijing (Jin 2003) and (1/51, Kim 2011), Shanghai (seven individuals, (Wu 2009)), Xi'an (1/34, Kim 2011), Jiangsu (Lu 2008), Wuhan (1/160), South China outside of Jiangsu, Anhui, Zhejiang, and Shanghai (1/65) and southern Fujian, Koreans in China (Xue 2006 and Katoh 2004), Manchus (Xue 2006, Katoh 2004, and Karafet 2001), Sibes (Xue 2006), and Kham Tibetans.

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