Henriëtte Amalia Maria von Anhalt-Dessau (Kleve, 16 August 1666 – Dietz an der Lahn, 18 April 1726) was the daughter of John George II, Prince of Anhalt-Dessau, and Henriëtte Catharina of Nassau and the granddaughter of Frederick Henry, Prince of Orange.

She married her cousin Henry Casimir II, Prince of Nassau-Dietz, in 1683. When Henry Casimir died in 1696, she became regent for their son became, John William Friso, who succeeded to his father's titles. Henriëtte Amalia van Anhalt-Dessau have died in 1727, at the age of 59 and was buried in Dietz.

Hendrik Casimir II and Henriëtte Amalia had nine children:

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