Hexestrol

Hexestrol

Clinical data
Routes of administration	Oral
Identifiers
IUPAC name 4-[4-(4-Hydroxyphenyl)hexan-3-yl]phenol
Synonyms	NSC-9894
CAS Number	84-16-2
PubChem CID	3606
ChemSpider	3480
Chemical and physical data
Formula	C18H22O2
Molar mass	270.36608 g/mol
3D model (Jmol)	Interactive image
SMILES CCC(C1=CC=C(C=C1)O)C(CC)C2=CC=C(C=C2)O
InChI InChI=1S/C18H22O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,17-20H,3-4H2,1-2H3 Key:PBBGSZCBWVPOOL-UHFFFAOYSA-N

Hexestrol (INN) (brand name Synestrol, Synoestrol, Estrifar, Estronal, numerous others), also known as hexanestrol, hexoestrol, and dihydrodiethylstilbestrol, is a synthetic, non-steroidal estrogen of the stilbestrol group related to diethylstilbestrol that was used to treat estrogen deficiency but is now no longer employed medically. Hexestrol has also been available and used in ester form, including as hexestrol diacetate, hexestrol dicaprylate, hexestrol diphosphate, and hexestrol dipropionate. Hexestrol has approximately 302% and 234% of the affinity of estradiol at the ERα and ERβ, respectively. Along with diethylstilbestrol, hexestrol is one of the most potent estrogens known.