The House of Joseph (sometimes referred to as the Tribe of Joseph) were the Old Testament tribes of Ephraim and Manasseh. Both of these tribes were descendants of Joseph's two sons, Ephraim and Manasseh, who are both first mentioned in . In Genesis Ephraim and Manasseh are taken to see a dying Jacob, who blesses Ephraim (the younger son) with his right hand and Manasseh with his left hand.
The house of Joseph is mentioned in the Bible several times, notably in ; ; ; and . There is also an allusion to the house of Joseph in .
Both the Samaritan sect and The Church of Jesus Christ of Latter-day Saints (LDS Church) claim Joseph as one of their ancient tribal patriarchs. In Latter Day Saint interfaith relations with Jews, the LDS Church sometimes calls its people "Joseph", whilst calling the Jews "Judah", emphasizing beliefs of close kinship and mutual sacred covenant. Latter Day Saints do not believe themselves to be exclusively descended from these specific tribes, but in their use of names they associate themselves most closely with specific dominant tribes. No denomination of Judaism affirms the Samaritan or LDS beliefs, nor similar beliefs adhered to by anyone else.
After translating the Book of Mormon and publishing it in 1830, Joseph Smith asked five associates to join in officially incorporating the Church of Christ on April 6, 1830 in the company of some 56 men and women in Fayette, New York. After suffering under persecution in several states, including a government-ordered expulsion from Missouri and the assassination of Joseph Smith by a mob in Illinois, Brigham Young was called to succeed Joseph Smith and led the Mormon pioneers to settle a large area now encompassed by the state of Utah and parts of Arizona, California, Nevada, Idaho, and Wyoming.