Huntingtin

HTT
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3IO6, 3IOU, 3LRH, 4FE8, 4FEB, 4FEC, 4FED, 2LD0, 2LD2, 3IO4, 3IOR, 3IOT, 3IOV, 3IOW, 4RAV
Identifiers
Aliases	HTT, HD, IT15, huntingtin
External IDs	OMIM: 613004 MGI: 96067 HomoloGene: 1593 GeneCards: HTT
Gene ontology Molecular function • profilin binding • dynactin binding • ion channel binding • p53 binding • transcription factor binding • protein binding • beta-tubulin binding • identical protein binding • dynein intermediate chain binding • kinase binding Cellular component • cytoplasm • late endosome • Golgi apparatus • nucleoplasm • protein complex • autophagosome • endoplasmic reticulum • centriole • cytoplasmic vesicle membrane • nucleus • dendrite • cytosol • axon Biological process • animal organ development • retrograde vesicle-mediated transport, Golgi to ER • Golgi organization • vesicle transport along microtubule • negative regulation of extrinsic apoptotic signaling pathway • establishment of mitotic spindle orientation • positive regulation of cilium assembly • positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity • apoptotic process • vocal learning • positive regulation of lipophagy • positive regulation of mitophagy • positive regulation of aggrephagy • regulation of phosphoprotein phosphatase activity Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3064	15194
Ensembl	ENSG00000197386	ENSMUSG00000029104
UniProt	P42858	P42859
RefSeq (mRNA)	NM_002111	NM_010414
RefSeq (protein)	NP_002102	n/a
Location (UCSC)	Chr 4: 3.07 – 3.24 Mb	Chr 5: 34.76 – 34.91 Mb
PubMed search

3IO6, 3IOU, 3LRH, 4FE8, 4FEB, 4FEC, 4FED, 2LD0, 2LD2, 3IO4, 3IOR, 3IOT, 3IOV, 3IOW, 4RAV

3064

15194

ENSG00000197386

ENSMUSG00000029104

P42858

P42859

NM_002111

NM_010414

...
Wikipedia