IKZF1

IKZF1

Identifiers

IKZF1, Hs.54452, IK1, IKAROS, LYF1, LyF-1, PPP1R92, PRO0758, ZNFN1A1, CVID13, IKAROS family zinc finger 1

External IDs

MGI: 1342540 HomoloGene: 55948 GeneCards: IKZF1

Genetically Related Diseases

acute lymphocytic leukemia,

Gene ontology
Molecular function	• transcription factor activity, sequence-specific DNA binding • transcription regulatory region DNA binding • DNA binding • protein binding • metal ion binding • nucleic acid binding
Cellular component	• cytoplasm • protein complex • nucleus • nuclear pericentric heterochromatin • nucleoplasm • nucleolus • intracellular membrane-bounded organelle
Biological process	• erythrocyte differentiation • cell cycle • multicellular organism development • mesoderm development • negative regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • lymphocyte differentiation • covalent chromatin modification
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE IKZF1 205039 s at tn.png

PBB GE IKZF1 216901 s at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


10320


22778


ENSG00000185811


ENSMUSG00000018654


Q13422


Q03267

RefSeq (mRNA)

NM_001220765 NM_001220766 NM_001220767 NM_001220768 NM_001220769
NM_001220770 NM_001220771 NM_001220772 NM_001220773 NM_001220774 NM_001220775 NM_001220776 NM_001291837 NM_001291838 NM_001291839 NM_001291840 NM_001291841 NM_001291842 NM_001291843 NM_001291844 NM_001291845 NM_001291846 NM_001291847 NM_006060

NM_001025597 NM_001301863 NM_001301865 NM_001301866 NM_001301868
NM_009578

RefSeq (protein)

NP_001207694 NP_001207696 NP_001207697 NP_001207699 NP_001207700
NP_001278766 NP_001278767 NP_001278768 NP_001278769 NP_001278770 NP_001278771 NP_001278772 NP_001278773 NP_001278774 NP_001278775 NP_001278776 NP_006051


n/a

Location (UCSC)

Chr 7: 50.3 – 50.41 Mb

Chr 11: 11.69 – 11.77 Mb

PubMed search

ENSG00000185811

ENSMUSG00000018654

NM_001220770
NM_001220771
NM_001220772
NM_001220773
NM_001220774
NM_001220775
NM_001220776
NM_001291837
NM_001291838
NM_001291839
NM_001291840
NM_001291841
NM_001291842
NM_001291843
NM_001291844
NM_001291845
NM_001291846
NM_001291847
NM_006060

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Wikipedia

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