IL13RA1

IL13RA1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3BPN, 3BPO, 4HWB, 5E4E
Identifiers
Aliases	IL13RA1, CD213A1, IL-13Ra, NR4, CT19, interleukin 13 receptor subunit alpha 1
External IDs	MGI: 105052 HomoloGene: 1198 GeneCards: IL13RA1
Gene location (Human) Chr. X chromosome (human) Band Xq24 Start 118,727,572 bp End 118,794,539 bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X A3.3|X 20.49 cM Start 36,112,110 bp End 36,171,259 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • cytokine receptor activity • protein binding Cellular component • integral component of membrane • interleukin-13 receptor complex • plasma membrane • membrane Biological process • cell surface receptor signaling pathway • cytokine-mediated signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3597	16164
Ensembl	ENSG00000131724	ENSMUSG00000017057
UniProt	P78552	O09030
RefSeq (mRNA)	NM_001560	NM_133990
RefSeq (protein)	NP_001551	NP_598751
Location (UCSC)	Chr X: 118.73 – 118.79 Mb	Chr X: 36.11 – 36.17 Mb
PubMed search

3BPN, 3BPO, 4HWB, 5E4E

3597

16164

ENSG00000131724

ENSMUSG00000017057

P78552

O09030

NM_001560

NM_133990

NP_001551

NP_598751

Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1), is a human gene.

The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

...
Wikipedia