Interleukin-13

IL13

Protein IL13 PDB 1ga3.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1GA3, 1IJZ, 1IK0, 3BPO, 3G6D, 3L5W, 3L5X, 3LB6, 4I77, 4PS4, 5E4E

Identifiers

IL13, IL-13, P600, interleukin 13

External IDs

OMIM: 147683 MGI: 96541 HomoloGene: 1649 GeneCards: IL13

Genetically Related Diseases

asthma, Hodgkin's lymphoma, psoriasis

Gene ontology
Molecular function	• cytokine activity • protein binding • cytokine receptor binding • interleukin-13 receptor binding
Cellular component	• cytoplasm • external side of plasma membrane • extracellular region • extracellular space
Biological process	• negative regulation of endothelial cell apoptotic process • negative regulation of complement-dependent cytotoxicity • movement of cell or subcellular component • negative regulation of transforming growth factor beta production • positive regulation of lung goblet cell differentiation • cell-cell signaling • response to mechanical stimulus • response to nicotine • positive regulation of release of sequestered calcium ion into cytosol • positive regulation of tyrosine phosphorylation of Stat6 protein • microglial cell activation • negative regulation of NAD(P)H oxidase activity • cellular response to mechanical stimulus • response to lipopolysaccharide • negative regulation of lung ciliated cell differentiation • positive regulation of ion transport • immune response • positive regulation of protein secretion • positive regulation of connective tissue growth factor production • positive regulation of pancreatic stellate cell proliferation • response to ethanol • inflammatory response • regulation of proton transport • signal transduction • positive regulation of smooth muscle cell proliferation • negative regulation of neuron death • positive regulation of immunoglobulin production • positive regulation of B cell proliferation • positive regulation of macrophage activation • positive regulation of mast cell degranulation • cellular response to cytokine stimulus
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE IL13 207844 at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


3596


16163


ENSG00000169194


ENSMUSG00000020383


P35225


P20109

RefSeq (mRNA)


NM_002188


NM_008355

RefSeq (protein)


NP_002179


NP_032381.1 NP_032381

Location (UCSC)

Chr 5: 132.66 – 132.66 Mb

Chr 11: 53.63 – 53.63 Mb

PubMed search

1GA3, 1IJZ, 1IK0, 3BPO, 3G6D, 3L5W, 3L5X, 3LB6, 4I77, 4PS4, 5E4E

ENSG00000169194

ENSMUSG00000020383

NP_032381.1
NP_032381

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Wikipedia

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