Interleukin 1 receptor antagonist

IL1RN

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1ILR, 1ILT, 1IRA, 1IRP, 2IRT

Identifiers

IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4, interleukin 1 receptor antagonist

External IDs

Genetically Related Diseases

Gene ontology
Molecular function	• interleukin-1 Type I receptor antagonist activity • interleukin-1, Type II receptor binding • protein binding • interleukin-1, Type I receptor binding • interleukin-1 Type II receptor antagonist activity • interleukin-1 receptor binding • cytokine activity • interleukin-1 receptor antagonist activity
Cellular component	• cytoplasm • vesicle • plasma membrane • intracellular • extracellular region • extracellular exosome • extracellular space
Biological process	• negative regulation of interleukin-1-mediated signaling pathway • lipid metabolic process • response to glucocorticoid • insulin secretion • acute-phase response • negative regulation of heterotypic cell-cell adhesion • negative regulation of cytokine-mediated signaling pathway • inflammatory response • immune response
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


3557


16181


ENSG00000136689


ENSMUSG00000026981


P18510


P25085

RefSeq (mRNA)


NM_000577 NM_173841 NM_173842 NM_173843 NM_001318914


NM_001039701 NM_001159562 NM_031167

RefSeq (protein)


NP_000568 NP_001305843 NP_776213 NP_776214 NP_776215


NP_001034790.1 NP_112444.1 NP_001034790 NP_001153034 NP_112444

Location (UCSC)

PubMed search