JNJ-5207852

JNJ-5207852

Names
Preferred IUPAC name 1-{3-[4-(Piperidin-1-ylmethyl)phenoxy]propyl}piperidine
Systematic IUPAC name 1-({4-[3-(Piperidin-1-yl)propoxy]phenyl}methyl)piperidine
Identifiers
3D model (JSmol)	Interactive image Interactive image
Abbreviations	JNJ-5207852
ChEBI	CHEBI:312531 N
ChemSpider	2046959 Y
IUPHAR/BPS	1256
MeSH	JNJ-5207852
PubChem CID	2766326
InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2 Y Key: PTKHFRNHJULJKT-UHFFFAOYSA-N Y
SMILES O(c1ccc(cc1)CN2CCCCC2)CCCN3CCCCC3 O(c1ccc(cc1)CN2CCCCC2)CCCN3CCCCC3
Properties
Chemical formula	C20H32N2O
Molar mass	316.480 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

JNJ-5207852 is a histamine antagonist selective for the H₃ subtype. It has stimulant and nootropic effects in animal studies, and has been suggested as a possible treatment for memory defects associated with epilepsy. JNJ-5207852 itself did not progress to clinical development due to poor pharmacokinetic characteristics, but the related compound JNJ-17216498 is currently in Phase II clinical trials for the treatment of narcolepsy.