JNJ-7777120

JNJ-7777120
Clinical data


Synonyms	1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
Identifiers
IUPAC name 5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-indole
CAS Number	459168-41-3^Y
PubChem CID	4908365
IUPHAR/BPS	1278
ChemSpider	4090750^N
ChEMBL	CHEMBL129198^N
ECHA InfoCard	100.164.683
Chemical and physical data
Formula	C₁₄H₁₆ClN₃O
Molar mass	277.749 g/mol
3D model (JSmol)	Interactive image
SMILES C3CN(C)CCN3C(=O)c(cc1c2)nc1ccc2Cl
InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3^N Key:HUQJRYMLJBBEDO-UHFFFAOYSA-N^N
^NY (what is this?)

JNJ-7777120 is a drug being developed by Johnson & Johnson Pharmaceutical Research & Development which acts as a potent and selective antagonist at the histamine H₄ receptor. It has anti-inflammatory effects, and has been demonstrated to be superior to traditional antihistamines in the treatment of pruritus (itching).