Jesús Antonio Guzmán Álvarez (born June 14, 1984) is a Venezuelan professional baseball player who is currently a free agent. He was signed by the Seattle Mariners in 2000 and played several seasons in minor league baseball before he appeared in the major leagues. He has played with the San Francisco Giants, San Diego Padres, Houston Astros and Hiroshima Toyo Carp.

Guzmán was signed by the Seattle Mariners as an undrafted free agent in 2000. He played in the Venezuelan leagues from 2001 through 2003 as a teenager. Guzmán came to the United States in 2004 and played with the Seattle High-A and Double-A affiliates through 2007 when he was granted free agency. The Oakland Athletics signed Guzmán as a minor league free agent, and he played for three Athletics minor league clubs in 2008 before again being granted free agency. He posted a .364 batting average with the Double-A Midland RockHounds, and a .237 average in a limited 59 at-bats with the Triple-A Sacramento River Cats, but his defense was a liability and he made 22 errors in 317 chances in 2008 while playing third and second base.

The San Francisco Giants signed Guzmán as a minor league free agent and invited him to spring training in 2009. He had an impressive spring, hitting .404 in Cactus League games, but in late March he was sent to learn to play first base in minor league games where his footwork on defense would not be as crucial. Guzmán began the 2009 season with the Triple-A Fresno Grizzlies, where he spent most of the season apart from a few short stints with the Major League club. He accumulated a .321 batting average and a .885 OPS in 115 games at Triple-A, playing first base almost exclusively.

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