KALRN

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1WFW

Identifiers

Aliases

KALRN, ARHGEF24, CHD5, CHDS5, DUET, DUO, HAPIP, TRAD, kalirin, RhoGEF kinase, kalirin RhoGEF kinase

External IDs

MGI: 2685385 HomoloGene: 57160 GeneCards: KALRN

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • guanyl-nucleotide exchange factor activity • metal ion binding • kinase activity • protein serine/threonine kinase activity • protein binding • ATP binding • Rho guanyl-nucleotide exchange factor activity • GTPase activator activity • Rac guanyl-nucleotide exchange factor activity
Cellular component	• cytoplasm • actin cytoskeleton • extracellular exosome • cytoskeleton • nucleoplasm • cytosol • postsynaptic density of dendrite
Biological process	• intracellular signal transduction • phosphorylation • ephrin receptor signaling pathway • nervous system development • protein phosphorylation • positive regulation of apoptotic process • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • vesicle-mediated transport • signal transduction • positive regulation of dendritic spine morphogenesis • behavioral response to cocaine • behavioral fear response • social behavior • regulation of protein localization to plasma membrane • positive regulation of GTPase activity • regulation of synaptic transmission, glutamatergic • memory • positive regulation of dendritic spine development • Rho protein signal transduction • neuromuscular junction development • lactation • adult locomotory behavior • response to mechanical stimulus • smooth muscle cell migration • maternal behavior • habituation • regulation of neuronal synaptic plasticity • smooth muscle cell proliferation • negative regulation of growth hormone secretion • maternal process involved in parturition • behavioral response to formalin induced pain • positive regulation of long-term synaptic potentiation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


8997


545156

Ensembl


ENSG00000160145


ENSMUSG00000061751

UniProt


O60229


A2CG49

RefSeq (mRNA)

NM_001024660 NM_003947 NM_007064 NM_001322988 NM_001322989
NM_001322990 NM_001322991 NM_001322992 NM_001322993 NM_001322994 NM_001322995 NM_001322996 NM_001322997 NM_001322998 NM_001322999 NM_001323000 NM_001323001


NM_001164268 NM_177357

RefSeq (protein)

NP_001019831 NP_001309917 NP_001309918 NP_001309919 NP_001309920
NP_001309921 NP_001309922 NP_001309923 NP_001309924 NP_001309925 NP_001309926 NP_001309927 NP_001309928 NP_001309929 NP_001309930 NP_003938 NP_008995


NP_001157740 NP_796331

Location (UCSC)

Chr 3: 124.08 – 124.73 Mb

Chr 16: 33.97 – 34.57 Mb

PubMed search

NM_001322990
NM_001322991
NM_001322992
NM_001322993
NM_001322994
NM_001322995
NM_001322996
NM_001322997
NM_001322998
NM_001322999
NM_001323000
NM_001323001

NM_001164268
NM_177357

...
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