KCNIP4

KCNIP4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3DD4
Identifiers
Aliases	KCNIP4, CALP, KCHIP4, potassium voltage-gated channel interacting protein 4
External IDs	MGI: 1933131 HomoloGene: 23528 GeneCards: KCNIP4
Gene ontology Molecular function • calcium ion binding • potassium channel regulator activity • potassium channel activity • voltage-gated ion channel activity • metal ion binding Cellular component • cytoplasm • cytosol • voltage-gated potassium channel complex • plasma membrane • endoplasmic reticulum • membrane Biological process • potassium ion transport • regulation of ion transmembrane transport • protein localization to plasma membrane • cardiac conduction • ion transport • regulation of potassium ion transmembrane transport • potassium ion transmembrane transport • transport • regulation of molecular function Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	80333	80334
Ensembl	n/a	ENSMUSG00000029088
UniProt	Q6PIL6	Q6PHZ8
RefSeq (mRNA)	NM_001035003 NM_001035004 NM_025221 NM_147181 NM_147182 NM_147183	NM_001199242 NM_001199243 NM_001199244 NM_001199245 NM_030265
RefSeq (protein)	NP_001030175 NP_001030176 NP_079497 NP_671710 NP_671711 NP_671712	NP_001186171.1 NP_001186172.1 NP_084541.3 NP_001186171 NP_001186172 NP_001186173 NP_001186174 NP_084541
Location (UCSC)	Chr 4: 20.73 – 21.95 Mb	Chr 5: 48.39 – 49.52 Mb
PubMed search

3DD4

80333

80334

n/a

ENSMUSG00000029088

Q6PIL6

Q6PHZ8

NM_147183

NM_001199242
NM_001199243
NM_001199244
NM_001199245
NM_030265

NP_671712

NP_001186173
NP_001186174
NP_084541

Kv channel-interacting protein 4 is a protein that in humans is encoded by the KCNIP4 gene.

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

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Wikipedia