KCNK18

KCNK18
Identifiers
Aliases	KCNK18, K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK, potassium two pore domain channel subfamily K member 18
External IDs	MGI: 2685627 HomoloGene: 133808 GeneCards: KCNK18
Gene ontology Molecular function • calcium-activated potassium channel activity • outward rectifier potassium channel activity • potassium channel activity • potassium ion leak channel activity Cellular component • integral component of membrane • plasma membrane • membrane • integral component of plasma membrane Biological process • potassium ion transport • cellular response to pH • ion transport • potassium ion export • potassium ion transmembrane transport • transport • regulation of ion transmembrane transport • stabilization of membrane potential Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	338567	332396
Ensembl	ENSG00000186795	ENSMUSG00000040901
UniProt	Q7Z418	Q6VV64
RefSeq (mRNA)	NM_181840	NM_207261
RefSeq (protein)	NP_862823	NP_997144.1 NP_997144
Location (UCSC)	Chr 10: 117.2 – 117.21 Mb	Chr 19: 59.22 – 59.24 Mb
PubMed search

338567

332396

ENSG00000186795

ENSMUSG00000040901

Q7Z418

Q6VV64

NM_181840

NM_207261

NP_862823

NP_997144.1
NP_997144

Potassium channel subfamily K member 18 (KCNK18), also known as TWIK-related spinal cord potassium channel (TRESK) or K_2P18.1 is a protein that in humans is encoded by the KCNK18 gene. K_2P18.1 is a potassium channel containing two pore-forming P domains.

A flaw in this gene could help trigger migraine headaches. If the gene does not work properly, environmental factors can more easily trigger pain centres in the brain and cause a severe headache.

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Wikipedia