KRT85

KRT85
Identifiers
Aliases	KRT85, ECTD4, HB5, Hb-5, K85, KRTHB5, hHb5, keratin 85
External IDs	HomoloGene: 37603 GeneCards: KRT85
Gene location (Human) Chr. Chromosome 12 (human) Band 12q13.13 Start 52,360,006 bp End 52,367,481 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • structural molecule activity Cellular component • intermediate filament • keratin filament • extracellular space • cytosol Biological process • epidermis development • keratinization • cornification Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3891	n/a
Ensembl	ENSG00000135443	n/a
UniProt	P78386	n/a
RefSeq (mRNA)	NM_002283 NM_001300810	n/a
RefSeq (protein)	NP_001287739 NP_002274	n/a
Location (UCSC)	Chr 12: 52.36 – 52.37 Mb	n/a
PubMed search		n/a

3891

n/a

ENSG00000135443

n/a

P78386

n/a

NM_002283
NM_001300810

n/a

NP_001287739
NP_002274

n/a

Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.

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