Kelley Cain (born May 16, 1989) is an American basketball center who last played for the Connecticut Sun of the WNBA. Born in Stone Mountain, Georgia, she went to St. Pius X Catholic High School (Georgia) and played collegiately for the Tennessee. Currently she plays for Güre Belediye Woman Basketball Club in İzmir, Turkey.

Cain was a member of the USA Women's U18 team which won the gold medal at the FIBA Americas Championship in Colorado Springs, Colorado. The event was held in July 2006, when the USA team defeated Canada to win the championship. Cain helped the team the gold medal, scoring 6.5 points per game. Her field goal percentage of 57.9% was second among all contestants, and her 1.75 blocks per game was tied for first (with Jayne Appel)

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She was selected in the first round of the 2012 WNBA Draft (7th overall) by the New York Liberty, while she was playing in Turkey for Güre Belediye Woman Basketball Club in İzmir.

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