Keratin 16

KRT16
Identifiers
Aliases	KRT16, CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK, PC1, keratin 16
External IDs	OMIM: 148067 MGI: 96690 HomoloGene: 21145 GeneCards: KRT16
Gene ontology Molecular function • structural constituent of cytoskeleton • protein binding • structural molecule activity Cellular component • extracellular exosome • cytoskeleton • intermediate filament • nucleus • cytosol Biological process • morphogenesis of an epithelium • hair cycle • keratinocyte migration • aging • cell proliferation • inflammatory response • negative regulation of cell migration • innate immune response • cytoskeleton organization • keratinocyte differentiation • epidermis development • intermediate filament cytoskeleton organization • establishment of skin barrier • keratinization • cornification Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3868	16666
Ensembl	ENSG00000186832	ENSMUSG00000053797
UniProt	P08779	Q9Z2K1
RefSeq (mRNA)	NM_005557	NM_008470 NM_001313958
RefSeq (protein)	NP_005548	NP_001300887.1 NP_032496.1 NP_001300887 NP_032496
Location (UCSC)	Chr 17: 41.61 – 41.62 Mb	Chr 11: 100.25 – 100.25 Mb
PubMed search

3868

16666

ENSG00000186832

ENSMUSG00000053797

P08779

Q9Z2K1

NM_005557

NM_008470
NM_001313958

NP_005548

NP_001300887.1
NP_032496.1
NP_001300887
NP_032496

Keratin 16 is a protein that in humans is encoded by the KRT16 gene.

Keratin 16 is a type I cytokeratin. It is paired with keratin 6 in a number of epithelial tissues, including nail bed, esophagus, tongue, and hair follicles. Mutations in the gene encoding this protein are associated with the genetic skin disorders pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

...
Wikipedia