This article contains a list of all Canadian Football League head coaches by regular season wins. This list is current through the close of the 2016 regular season.
This list also includes coaches who coached in the CFL's predecessor leagues, the Interprovincial Rugby Football Union (CFL East Division) and the Western Interprovincial Football Union (CFL West Division).
Wally Buono is the all-time leader in both wins and losses and he is also the active leader in the categories following his return to coaching in 2016. Ten coaches have more than 100 wins and only Buono and Don Matthews have more than 200.
As of 2016, the active head coach closest to surpassing 100 wins is Marc Trestman, who has 59 wins and 31 losses.