Lloviu virus
| Lloviu virus (LLOV) | |
|---|---|
| Virus classification | |
| Group: | Group V ((−)ssRNA) |
| Order: | Mononegavirales |
| Family: | Filoviridae |
| Genus: | Cuevavirus |
| Species: | Lloviu cuevavirus |
Lloviu virus (LLOV) is an uncultured virus distantly related to the well-known pathogens Ebola virus and Marburg virus.
Lloviu virus (abbreviated LLOV) is the sole member of the species Lloviu cuevavirus, which is included genus Cuevavirus, family Filoviridae, order Mononegavirales. The name Lloviu virus is derived from Cueva del Lloviu, the name of a Spanish cave in which it was first discovered.
Lloviu virus is pronounced j’ɔːvjuː vaɪrəs (IPA). According to the rules for taxon naming established by the International Committee on Taxonomy of Viruses (ICTV), the name Lloviu virus is always to be capitalized (because "Lloviu" is a proper noun), but is never italicized, and may be abbreviated (with LLOV being the official abbreviation).
A virus that fulfills the criteria for being a member of the species Lloviu cuevavirus is a Lloviu virus if it has the properties of Lloviu cuevaviruses and if its genome diverges from that of the prototype Lloviu cuevavirus, Lloviu virus variant Bat86 (LLOV/Bat86), by ≤10% at the nucleotide level.
LLOV was discovered in 2002 in Schreibers's long-fingered bats (species Miniopterus schreibersii) found dead in Cueva del Lloviu, Asturias, Spain, as well as in caves in Spanish Cantabria and in caves in France and Portugal. It has not yet been proven that the virus is the etiological agent of a novel bat disease, but healthy Schreibers' long-fingered bats were not found to contain traces of the viruses, thereby at least suggesting that the virus may be pathogenic for certain bats. Necropsies of dead bats did not reveal macroscopic pathology, but microscopic examination suggested viral pneumonia. Cueva del Lloviu is frequented by tourists, yet no human infections or disease has ever been observed, suggesting that LLOV is the second filovirus not pathogenic for humans (the first one being Reston virus (RESTV)).
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