Lymphotoxin beta receptor

LTBR
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1RF3, 4MXW
Identifiers
Aliases	LTBR, CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3, lymphotoxin beta receptor
External IDs	OMIM: 600979 MGI: 104875 HomoloGene: 1753 GeneCards: LTBR
Gene ontology Molecular function • protein binding • tumor necrosis factor-activated receptor activity • identical protein binding • ubiquitin protein ligase binding Cellular component • integral component of membrane • membrane • plasma membrane • integral component of plasma membrane Biological process • myeloid dendritic cell differentiation • tumor necrosis factor-mediated signaling pathway • positive regulation of JNK cascade • multicellular organism development • cellular response to mechanical stimulus • response to lipopolysaccharide • regulation of cell proliferation • positive regulation of extrinsic apoptotic signaling pathway • inflammatory response • viral process • signal transduction • apoptotic process • immune response • positive regulation of I-kappaB kinase/NF-kappaB signaling • hematopoietic or lymphoid organ development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4055	17000
Ensembl	ENSG00000111321	ENSMUSG00000030339
UniProt	P36941	P50284
RefSeq (mRNA)	NM_001270987 NM_002342	NM_010736
RefSeq (protein)	NP_001257916 NP_002333	NP_034866.1 NP_034866
Location (UCSC)	Chr 12: 6.38 – 6.39 Mb	Chr 6: 125.31 – 125.31 Mb
PubMed search

1RF3, 4MXW

4055

17000

ENSG00000111321

ENSMUSG00000030339

P36941

P50284

NM_001270987
NM_002342

NM_010736

NP_001257916
NP_002333

NP_034866.1
NP_034866

Lymphotoxin beta receptor (LTBR), also known as tumor necrosis factor receptor superfamily member 3 (TNFRSF3), is a cell surface receptor for lymphotoxin involved in apoptosis and cytokine release. It is a member of the tumor necrosis factor receptor superfamily.

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Wikipedia