MMP-9

MMP9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GKC, 1GKD, 1ITV, 1L6J, 2OVX, 2OVZ, 2OW0, 2OW1, 2OW2, 4H1Q, 4H2E, 4H3X, 4H82, 4HMA, 4JIJ, 4JQG, 4WZV, 4XCT, 5CUH, 5I12
Identifiers
Aliases	MMP9, CLG4B, GELB, MANDP2, MMP-9, 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B, matrix metallopeptidase 9
External IDs	MGI: 97011 HomoloGene: 3659 GeneCards: MMP9
Gene location (Human) Chr. Chromosome 20 (human) Band 20q13.12 Start 46,008,908 bp End 46,016,561 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2 H3|2 85.27 cM Start 164,940,780 bp End 164,955,850 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • collagen binding • zinc ion binding • metal ion binding • peptidase activity • protein binding • identical protein binding • hydrolase activity • metallopeptidase activity • endopeptidase activity • serine-type endopeptidase activity • metalloendopeptidase activity Cellular component • extracellular matrix • proteinaceous extracellular matrix • extracellular exosome • extracellular space • tertiary granule lumen • ficolin-1-rich granule lumen • extracellular region Biological process • skeletal system development • negative regulation of cation channel activity • positive regulation of protein phosphorylation • endodermal cell differentiation • negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway • ossification • negative regulation of intrinsic apoptotic signaling pathway • ephrin receptor signaling pathway • extracellular matrix disassembly • negative regulation of apoptotic process • proteolysis • macrophage differentiation • positive regulation of keratinocyte migration • positive regulation of apoptotic process • collagen catabolic process • positive regulation of release of cytochrome c from mitochondria • positive regulation of receptor binding • positive regulation of DNA binding • positive regulation of epidermal growth factor receptor signaling pathway • embryo implantation • leukocyte migration • positive regulation of vascular smooth muscle cell proliferation • extracellular matrix organization • positive regulation of cell migration • neutrophil degranulation • cellular response to reactive oxygen species • cellular response to cadmium ion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4318	17395
Ensembl	ENSG00000100985	ENSMUSG00000017737
UniProt	P14780	P41245
RefSeq (mRNA)	NM_004994	NM_013599
RefSeq (protein)	NP_004985	NP_038627
Location (UCSC)	Chr 20: 46.01 – 46.02 Mb	Chr 20: 164.94 – 164.96 Mb
PubMed search

1GKC, 1GKD, 1ITV, 1L6J, 2OVX, 2OVZ, 2OW0, 2OW1, 2OW2, 4H1Q, 4H2E, 4H3X, 4H82, 4HMA, 4JIJ, 4JQG, 4WZV, 4XCT, 5CUH, 5I12

4318

17395

ENSG00000100985

ENSMUSG00000017737

...
Wikipedia