MSI1

MSI1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1UAW, 2MSS, 2MST, 2RS2
Identifiers
Aliases	MSI1
External IDs	MGI: 107376 HomoloGene: 55657 GeneCards: MSI1
Gene ontology Molecular function • single-stranded RNA binding • nucleic acid binding • poly(U) RNA binding • identical protein binding • RNA binding Cellular component • cytoplasm • polysome • nucleus Biological process • nervous system development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4440	17690
Ensembl	ENSG00000135097	ENSMUSG00000054256
UniProt	O43347	Q61474
RefSeq (mRNA)	NM_002442	NM_008629
RefSeq (protein)	NP_002433	NP_032655.1 NP_032655
Location (UCSC)	Chr 12: 120.34 – 120.37 Mb	Chr 5: 115.43 – 115.46 Mb
PubMed search

1UAW, 2MSS, 2MST, 2RS2

4440

17690

ENSG00000135097

ENSMUSG00000054256

O43347

Q61474

NM_002442

NM_008629

NP_002433

NP_032655.1
NP_032655

RNA-binding protein Musashi homolog 1 is a protein that in humans is encoded by the MSI1 gene.

This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.

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