MYD88

MYD88

Toll-like receptor pathways revised.jpg

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2JS7, 2Z5V, 3MOP, 4DOM, 4EO7

Identifiers

MYD88, MYD88D, myeloid differentiation primary response 88

External IDs

OMIM: 602170 MGI: 108005 HomoloGene: 1849 GeneCards: MYD88

Gene ontology
Molecular function	• death receptor binding • protein binding • TIR domain binding • identical protein binding • protein self-association
Cellular component	• cytosol • plasma membrane • endosome membrane • cytoplasm • nucleus
Biological process	• response to interleukin-1 • immune system process • negative regulation of apoptotic process • MyD88-dependent toll-like receptor signaling pathway • toll-like receptor signaling pathway • cell surface receptor signaling pathway • cellular response to mechanical stimulus • regulation of inflammatory response • positive regulation of interleukin-6 production • positive regulation of I-kappaB kinase/NF-kappaB signaling • toll-like receptor 9 signaling pathway • positive regulation of interleukin-17 production • inflammatory response • 3'-UTR-mediated mRNA stabilization • positive regulation of type I interferon production • positive regulation of interleukin-23 production • signal transduction • defense response to Gram-positive bacterium • positive regulation of NF-kappaB transcription factor activity • apoptotic process • innate immune response
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE MYD88 209124 at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


4615


17874


ENSG00000172936


ENSMUSG00000032508


Q99836


P22366

RefSeq (mRNA)


NM_001172566 NM_001172567 NM_001172568 NM_001172569 NM_002468


NM_010851

RefSeq (protein)


NP_001166037 NP_001166038 NP_001166039 NP_001166040 NP_002459


NP_034981.1 NP_034981

Location (UCSC)

Chr 3: 38.14 – 38.14 Mb

Chr 9: 119.34 – 119.34 Mb

PubMed search

2JS7, 2Z5V, 3MOP, 4DOM, 4EO7

ENSG00000172936

ENSMUSG00000032508

NM_001172566
NM_001172567
NM_001172568
NM_001172569
NM_002468

NP_001166037
NP_001166038
NP_001166039
NP_001166040
NP_002459

...
Wikipedia

...