MYOM1

MYOM1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2R15, 2Y23, 2Y25, 3RBS
Identifiers
Aliases	MYOM1, SKELEMIN, myomesin 1
External IDs	MGI: 1341430 HomoloGene: 31196 GeneCards: MYOM1
Gene ontology Molecular function • structural constituent of muscle • protein binding • protein homodimerization activity • identical protein binding • actin filament binding • muscle alpha-actinin binding • structural molecule activity conferring elasticity • kinase binding Cellular component • cytoplasm • myosin filament • sarcomere • striated muscle myosin thick filament • Z disc • M band Biological process • muscle contraction • extraocular skeletal muscle development • striated muscle contraction • actin filament organization • sarcomere organization • striated muscle myosin thick filament assembly • positive regulation of gene expression • protein kinase A signaling • positive regulation of protein secretion Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8736	17929
Ensembl	ENSG00000101605	ENSMUSG00000024049
UniProt	P52179	Q62234
RefSeq (mRNA)	NM_003803 NM_019856	NM_001083934 NM_010867
RefSeq (protein)	NP_003794 NP_062830	NP_001077403 NP_034997
Location (UCSC)	Chr 18: 3.07 – 3.22 Mb	Chr 17: 71.02 – 71.13 Mb
PubMed search

2R15, 2Y23, 2Y25, 3RBS

8736

17929

ENSG00000101605

ENSMUSG00000024049

P52179

Q62234

NM_003803
NM_019856

NM_001083934
NM_010867

NP_003794
NP_062830

NP_001077403
NP_034997

Myomesin-1 is a protein that in humans is encoded by the MYOM1 gene. Myomesin-1 is expressed in muscle cells and functions to stabilize the three-dimensional conformation of the thick filament. Embryonic forms of Myomesin-1 have been detected in dilated cardiomyopathy.

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