Maebashi Domain (前橋藩 Maebashi-han?) was a feudal domain under the Tokugawa shogunate of Edo period Japan, located in Kōzuke Province (modern-day Gunma Prefecture), Japan. It was centered on Maebashi Castle in what is now part of the city of Maebashi, Gunma.
Maebashi was the location of an important fortification in the Sengoku period on a strategic junction of the Tone River with the main highway from Edo to Echigo Province and the Sea of Japan with the Nakasendō highway connecting Edo with Kyoto. The area was hotly contested between the Uesugi clan and the Takeda and Odawara Hōjō clans.
After Tokugawa Ieyasu took control over the Kantō region in 1590, he assigned the area to his trusted general, Hiraiwa Chikayoshi, with revenues of 33,000 koku. Following the establishment of the Tokugawa shogunate, the Hiraiwa were transferred to Kōfu Castle and were replaced by a branch of the Sakai clan, formerly daimyo of Kawagoe Domain. The Sakai ruled over nine generations from 1601 to 1749, during which time the domain was gradually enlarged to 150,000 koku. The 2nd daimyo, Sakai Tadayo and 4th daimyo, Sakai Tadakiyo served as tairō within the shogunal administration.